CACS houses several research laboratories and groups that carry out cutting-edge research in Computer Science and Engineer:

• BioInformatics
• CajunBot
• Computer Architecture & Networking (CAN)
• FPGA & Reconfigurable Computing
• Integrated Wireless Information Network (iWIN)
• Internet Computing (LINC)
• Micro/Nano-electronic Embedded Computing
• Neurocomputing
• Software Research
• Virtual Reality
• VLSI and SoC
• Wireless Systems and Performance Engineering Research (WiSPER)